General description
Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Anti-Thyroglobulin, combined with TTF1 are demonstrable by immunohistochemistry assay in the majority of thyroid neoplasms. A panel of antibodies for Thyroglobulin, TTF1, CK-7, CK19, and CK20 is useful when thyroid is the possible primary site of a metastatic tumor.
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
Linkage
Thyroglobulin Positive Control Slides, Product No. 340S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes
For Technical Service please contact: 800-665-7284 or email: [email protected]
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Quality
This product has met the following criteria to qualify for the following awards: